I would tend to agree that there's not a huge difference between Denoise and NN, Neat Image, or other decent noise reduction programs when dealing with light noise removal. If you already use one of these, and need to remove very light blue-sky noise or lower ISO noise, I wouldn't see enough difference to switch either.
Where I've found Denoise to jump significantly ahead of NoiseNinja, Helicon, and Neat Image at least for me, it is in extreme high ISO NR. When dealing with RAW or JPEG photos shot at ISO6400, 12800, or more, in extremely dark, underexposed conditions, the removal of noise while retaining detail is nothing short of amazing, as well as nice touches like black level correction. For those in doubt on Denoise's ability, try it out on a really nasty noisy photo or extremely high ISO.
I'd love to see InFocus live up to the samples they've shown - maybe future updates might make it possible to achieve those results. So far though, my results are so far from anything close to what they showed in their samples that it just doesn't justify itself for me. Essentially, only the sharpening seems to be of any value, and it doesn't really seem to sharpen any better than other sharp tools. Until I can get the focus blur correction to work as advertised, I won't be buying this product.