I've given this a lot more thought and am still no closer to deciding which would be the better option for me and I think therein lies the root of disagreement. The 2 lenses we have been looking at over the last posts are very different beasts and whilst being in the same price range both have their strengths and weaknesses.
The Tamron has a good focal length range, gives sharp images at full-frame and with the VC is hand-holdable. For my own use, the zoom would be very useful especially for video.
The Canon 400 f5.6 is very sharp, allowing for hard cropping of photos. It doesn't have IS which is very important for some but more significantly it is a prime not a zoom.
Regardless of differences of opinion over the sharpness of the lens with extender, both the Canon and Tamron function well at roughly 560mm and there is very little difference in aperture speed either. The caveat with the Canon, of course, is that AF would function with live-view only with the Canon bodies from 70D and down - I am guessing here but think it would AF with 5D mkiii and up?? The Tamron, however, does seem to perform much better with the full-frame bodies too.
Honestly, I think that the only way anybody could be 100% certain which of the lenses suits their needs most would be to actually use them both. I think I am struggling because I could use the strengths of both lenses, the Tamron's zoom and the Canon's sharpness for cropping would both be hugely beneficial to me.
And finally, it's grey and dark again so that's another weekend wasted
Edit: and now it's raining again!